Hi Madhav,
Create condition record for message type NEU in transaction NACE (EF PO) or Transaction NACR with unique key combination ex.with any one of doc type (or) purorg &edi vendor etc
Note: SAP checks for matching valid condition record for message types in the order of tables maintained in access sequence of that message type. SAP picks message type from first valid condition record. If SAP founds two valid condition records for different message types then both messages will trigger. So you maintain the condition record accordingly..
Best Regards
Satish